Abstract

Objective: To investigate quality of life in children with autism spectrum disorder.This study aimed to evaluate the validity of existing QoL questionnaires for use with children with ASD aged 8–12 years. Method 200 children with autism spectrum disorder (male: 118, female: 82; 2~4 years old: 80, 5~7 year old: 87, 8~12 years old: 33) and 120 normal children (control group) are brought into this study. Separate path analyses were performed to evaluate models of QOL and Intelligent evaluation. the PedsQL (Pediatric Quality of Life Inventory) as robust measures used with children with neurodevelopmental disorders.Results In the study,The test group had lower scores on the PedsQL4.0 universality Core scale, in comparison with the control group. Behaviour problems had a negative indirect effect on Community adaptation, mental health and school performance. And a lower intelligence-related quality of life for children with autism spectrum disorder and clinically significant autistic symptoms in comparison with children and fewer symptoms.The quality of life children with autism spectrum disorder group was lower than normal group in the scores of physical functioning were(62.30 ± 25.05),emotional functioning were(53.57 ± 26.69),social functioning were(44.63 ± 27.91)， and school functioning(38.69 ± 30.60).The totals cores of PedsQL were(49.86 ± 23.32),with the difference being significant(90.16±13.32、79.09±19.56、86.39±15.45、82.75±16.03、85.23 ±14.2，P<0.01).

Conclusions Results suggest greater impairment in adaptive functioning and emotional disorders. For high-functioning children with autism spectrum disorder, potential positive development played significant roles in rehabilitation, to achieve and maintain the best level of intervention.the severity of the disorder and social support coping strategies were related with Life self-care ability and adaptation, coping with Intelligent obstacle seriously .Physicians are encouraged to evaluate for early treatment in the overall care plan.

  Key words:      children with autism spectrum disorder ; quality of life ；PedsQL4.0;evaluation